Question

Sickle cell anemia is known to run in a family. A pedigree chart for this family is shown below. The parents are shown at the top and from left to right appear as a half-shaded circle labeled 1 next to a half-shaded square labeled 2. The two are connected by a straight line. Below the parent pair is a vertical straight line connecting to the next row of circles and squares which are the offspring. Starting from left an unshaded square labeled 1, half-shaded circle labeled 2, another half-shaded circle labeled 3, and a completely shaded square are shown labeled 4. All of these are also connected by a horizontal straight line. What best describes offspring 4?

Answer 1

In a pedigree chart, male is represented by a square and female a circle. Different generations in a family are lined up with the oldest at the top.  Shading represents the disease with half shade means a carrier and full shade means having the disease.

Based on the description, offspring 4 is represented by a completely shaded square so he is a male with sickle cell anemia.

Answer 2

Ans is a male having the disease.