Remains the same: proton pumping rate, electron transport rate, rate of oxygen uptake
Decreases or goes to zero: Rate of ATP synthesis, size of the proton gradient
<span>(Gramicidin causes membranes to become very leaky to protons, so that a proton gradient cannot be maintained and ATP synthesis stops. However, the leakiness of the membrane has no effect on the ability of electron transport to pump protons. Thus, the rates of proton pumping, electron transport, and oxygen uptake remain unchanged.)</span>
Function of an enzyme is to lower reaction's activation energy and to increase speed of a reaction, but to make it happen, enzyme and substrate must fit spatially. The shape of an enzyme is essential to make enzyme-substrate complex - if active site of an enzyme doesn't fit to substrate, there won't be a enzyme-catalised reaction.
