Question

A client with ovarian cancer is ordered hydroxyurea, an antimetabolite drug. Antimetabolites are a diverse group of antineoplastic agents that interfere with various metabolic actions of the cell. What mechanism of action do antimetabolites interfere with?

Answer 1

Answer:

Normal cellular processes during the S phase of the cell cycle.

Explanation:

Antimetabolites are drugs that affect one or more enzymes which are important for DNA synthesis by acting as a substitute to the main metabolites that would be used in the normal metabolism.

Antimetabolites also act during the S phase of the cell cycle thereby contributing to cell destruction.

While Antineoplastic antibiotic agents interfere with one or more stages of the synthesis of RNA, DNA, or both which prevent normal cell growth and reproduction of the cell.