Answer:
D. GGACCGTCGATCCTT
Explanation:
Mutation refers to any change in the nucleotide sequence of a gene. Mutation can be of different types depending on how it occurs. According to the question, an INVERSION mutation is a type of mutation in which a segment of a gene gets broken off and reattached in another way on the same DNA. Hence, the only change in inversion mutation is the arrangement of the nucleotide bases on the gene.
Considering the nucleotide sequence: GGACCGTCGATCTTC, the sequence that describes an occurrence of inversion mutation is: GGACCGTCGATCCTT because the segment TTC in the original sequence has been rearranged as CTT in the mutated sequence.
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Answer:
(E) Phosphoglucose isomerase (phosphohexose isomerase or glucose-6-phosphate isomerase)
Explanation:
Glyocolysis is break down of glucose into pyruvate.
Isomerization:The second step of glycolysis involves the conversion of glucose-6-phosphate to fructose-6-phosphate (F6P). This reaction occurs with the help of the enzyme phosphoglucose isomerase (PI). As the name of the enzyme suggests, this reaction involves an isomerization reaction.
Yeast mutant lacking phopshoglucose isomerase unable to performed this step and that's why it unable to grow in media containing glucose while in fructose break down this step is not required so it is able to grow in media containing fructose.
Deletion of phosphoglucose isomerase, prevents growth on glucose; therefore, phosphoglucose isomerase mutant is able to grown in a fructose medium.