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Mandarinka [93]
3 years ago
10

Calculate the number of ATP generated from one saturated 10 ‑carbon fatty acid. Assume that each NADH molecule generates 2.5 ATP

and that each FADH2 molecule generates 1.5 ATP .
Chemistry
1 answer:
larisa86 [58]3 years ago
6 0

Answer:

Total ATP molecules produced = 66 molecules of ATP

Explanation:

A 10-carbon fatty acid when it has undergone complete oxidation will yield 5 acetyl-CoA molecules and 4 FADH₂ and 4 NADH molecules each. Each of the 5 acetyl-CoA molecules enters into the citric acid cycle and is completely oxidized to yield further ATP and  FADH₂ and NADH molecules.

The total yield of ATP in the various enzymatic step is calculated below:

Acyl-CoA dehydrodenase = 4 FADH₂

β-Hydroxyacyl-CoA dehydrogenase = 4 NADH

Isocitrate dehydrogenase = 5 NADH

α-Ketoglutarate dehydrogenase = 5 NADH

Succinyl-CoA synthase = 5 ATP (from substrate-level phosphorylation of GDP)

Succinate dehydrogenase = 5 FADH₂

Malate dehydrogenase = 5 NADH

Total ATP  from FADH₂ molecoles = 9 * 1.5 = 13.5

Total NADH molecules = 19 * 2.5 = 47.5

Total ATP molecules produced = 13.5 + 47.5 + 5

Total ATP molecules produced = 66 molecules of ATP

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