This question is not really stated clearly can you retype it?
ANSWER: PYROGENS; HYPOTHALAMUS
EXPLANATION: During invasion of foreign agents into the body system. The body acts in defense to the invading microbes, this response to foreign body causes inflammation, fever, or abnormal high blood temperature.
However, Leukocytes and macrophages that are present in the surrounding cell, that are exposed to the invading microorganism will secrete PYROGENS which will help to regulate the body's temperature, located in the HYPOTHALAMUS of the brain.
Macronutrients- Carbohydrates.