Answer:
passively diffuses down its concentration gradient through the endothelial cell plasma membrane out of the cell and then passiveley diffuses through the plasma membrane into the cytoplasm of the smooth muscle cell, where it acts to decrease contraction.
Explanation:
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At first, we must consider that 
and 
, passively diffuses through membranes. As it is produced by an enzyme and accumulates in the endothelial cell cytosol, passively diffuses down its concentration gradient through the endothelial cell plasma membrane out of the cell and then passiveley diffuses through the plasma membrane into the cytoplasm of the smooth muscle cell, where it acts to decrease contraction.
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Ionic bonds usually occur between metal and nonmetal ions. For example, sodium (Na), a metal, and chloride (Cl), a nonmetal, form an ionic bond to make NaCl. In a covalent bond, the atoms bond by sharing electrons. Covalent bonds usually occur between nonmetals.
