Answer:
Four possible isomers (1–4) for the natural product essramycin. The structure of compound 1 was attributed to essramycin by 1H NMR, 13C NMR, HMBC, HRMS, and IR experiments.
Explanation:
Three synthetic routes were used to prepare all four compounds (Figure 2A). All three reactions utilize 2-(5-amino-4H-1,2,4-triazol-3-yl)-1-phenylethanone (5) as the precursor, whereas each uses different esters (6–8) to construct the pyrimidinone ring. Isomer 1 was prepared by reaction A, which used triazole 5 and ethyl acetoacetate (6) in acetic acid. This was the reaction used in syntheses of essramycin by the Cooper and Moody laboratories.3,4 Reaction B produced compound 2 (minor product) and compound 3 (major product), which were separated chromatographically. This reaction allowed reagent 5 to react with ethyl 3-ethoxy-2-butenoate (7) in the presence of sodium in methanol, under reflux for 24 h. Compound 4 was prepared by reaction C, which was obtained by reflux of 5 and methyl 2-butynoate (8) in n-butanol.
Answer:
heart I think also I'm so sorry if I get you this wrong I think membrane not sure tell me what was the right answer but I think membrane.
Answer:
In order to determine unequivocally which of the peaks represent Aldrin, I would run the pure sample through the chromatography equipment.
Explanation:
Gas chromatography is a technique that separates molecules based on their volatility and interaction with both the stationary phase.
The peaks on the chromatogram show how long a substance took to leave the column. Since each different substance substance will leave the column at a different time, each peak can be attributed to a substance.
Therefore, to know which of the 6 peaks represent Aldrin, it is necessary to run the pure Aldrin in the chromatography equipment and see the time of the peak. Then you just need to compare both chromatograms and indentify Aldrin.
Answer:
x = -3
Explanation:
8(6x + 4) = -112
Divide both sides by 8.
6x + 4 = -14
Subtract 4 from both sides.
6x = -18
Divide both sides by 6.
x = -3
It always points towards the products.
