Answer:
1. Someone in the United States has a stroke every 40 seconds.
2. Every year, more than 795,000 people in the United States have a stroke.
3. In the year of 2018, 1 in every 6 deaths from cardiovascular disease was due to stroke.
Answer:
c. Pyridostigmine binds to the acetylcholinesterase active site and prevents sarin from binding to and modifying the enzyme active site.
Explanation:
Sarin is a toxic compound which inhibits acetylcholinesterase enzyme. This enzyme degrades the neurotransmitter acetylcholine after the required muscle cell stimulation. In absence of its activity, acetylcholine is not degraded and the muscle cells are stimulated uncontrollably. The muscles are not able to relax which ultimately proves fatal for the victim.
Pyridostigmine is also an acetylcholinesterase inhibitor like Sarin. However its period of inhibition is short compared to organophosphorus inhibitors like sarin. It competes with sarin and replaces it in the active site of acetylcholinesterase. The enzyme is still inhibited but for a shorter time as compared to inhibition by Sarin. Hence after sometime, it becomes functional again and resumes its normal activity. Acetycholine starts getting degraded relaxing the muscles.
Explanation:
Pancreas functions as both endocrine and exocrine gland. Hence, called as dual function gland or a mixed gland. Exocrine part of pancreas secretes digestive enzymes while, its endocrine part (islets of Langerhans) produce two hormones, i.e. insulin and glucagon.
