<span>The answer is curie.
</span>
Look out for angioedema (like hives but a deeper swelling due to an allergic reacrion), bleeding (such as intracranial, gastrointestinal and genitourinal hemorrhaging) and adverse reactions to drugs. Nausea, blood pressure spikes, severe headaches, acute hypertsnsion, etc are other signs of negative reacrions to iv t-pa as well.
This reaction is called silioconic
Anion is an atom with a negative charge
so in this case it woulld be O2-