Binding of a signaling molecule to ligand-gated ion channel leads directly to a change in the distribution of ions on opposite sides of the membrane
<u>Explanation:</u>
The ligand-gated-ion-channel is trans membrane protein buildings that conduction course through the channel pores in light of the official of a neurotransmitter. They are not quite the same as voltage - gated - ion - channels, which are delicate to film possibilities, and G-protein coupled receptors (GPCR's), which utilize second messengers.
These ion channels, additionally ordinarily referred to as ionotropic receptors, are a gathering of trans membrane -ion-channel proteins which open to permit ions, for example, 
and potentially 
to go through the layer in light of the official of a synthetic errand person, for example, a neurotransmitter.
Answer:
The acceleration of the cart is 1.0 m\s^2 in the negative direction.
Explanation:
Using the equation of motion:
Vf^2 = Vi^2 + 2*a*x
2*a*x = Vf^2 - Vi^2
a = (Vf^2 - Vi^2)/ 2*x
Where Vf is the final velocity of the cart, Vi is the initial velocity of the cart, a the acceleration of the cart and x the displacement of the cart.
Let x = Xf -Xi
Where Xf is the final position of the cart and Xi the initial position of the cart.
x = 12.5 - 0
x = 12.5
The cart comes to a stop before changing direction
Vf = 0 m/s
a = (0^2 - 5^2)/ 2*12.5
a = - 1 m/s^2
The cart is decelerating
Therefore the acceleration of the cart is 1.0 m\s^2 in the negative direction.
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