Consider an animal cell in which motor proteins in the kinetochores normally pull the chromosomes along the kinetochore microtub
ules during mitosis. Suppose, however, that during metaphase, this cell was treated with an inhibitor that blocks the function of the motor proteins in the kinetochore, but allows the kinetochore to remain attached to the spindle. The inhibitor has no effect on any other mitotic process, including the function of the nonkinetochore microtubules.Answer yes or no to the following three questions concerning this animal cell that has been treated with the inhibitor:1. Will this cell elongate during mitosis? A / B.2. Will the sister chromatids separate from each other? A / B.3. Will the chromosomes move to the poles of the cell? A / B.A. noB. yes
The correct answer is "yes, yes, no" or "B, B, A".
Explanation:
In the hypothetical situation stated in the question, an inhibitor blocks the function of the motor proteins in the kinetochore, but allows the kinetochore to remain attached to the spindle. The animal cells treated with this inhibitor would be able to elongate during mitosis, their sister chromatids would separate from each other but the chromosomes would not move to the poles of the cell. The inhibitor only action is to block the function of the motor proteins, and since the motor protein function is to move the chromosomes to the poles of the cells, this will be the only activity that will be affected during cell's mitosis.
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The molecules that bind cellular respiration enzymes act as signals, giving the enzyme information about the cell's energy state. ATP and ADP are examples of molecules that regulate cellular respiration enzymes. ATP, for instance, is a "stop" signal: high levels mean that the cell has enough ATP and does not need to make more through cellular respiration.
This is a case of feedback inhibition in which a product feeds back to shut down its pathways.
