All of those can produce happy chemicals which cause your brain to become dependent. The side effects can be life-threatening but if it makes your brain irrationally happy then it doesn't matter
<h3><u><em>Why do some substances dissolve in water and others don't? It has to do with the structure of the water molecule. Oxygen has a greater attraction for electrons, so the shared electrons (bonding electrons) spend more time close to oxygen then to either of the hydrogens.</em></u></h3>
