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https://www.chemicool.com/
Ibuprofen is synthesized by reacting ethyl 2-(4-isobutylphenyl)acetate with base, the base abstracts the acidic proton and enolate is formed which on reaction with diethyl carbonate generates diethyl 2-(4-isobutylphenyl)malonate
(A). diethyl 2-(4-isobutylphenyl)malonate on treatment with Base again looses the acidic proton and forms enolate. The enolate with treatment with Methyl Iodide yields diethyl 2-(4-isobutylphenyl)-2-methylmalonate
(B). diethyl 2-(4-isobutylphenyl)-2-methylmalonate on
hydrolysis give
Ibuprofen.
B,Si,Ge,As,Sb,Te, and At are all the metalloids on the periodic table of elements.
T K = ºC + 273
T = 63 + 273
T = 336 K
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Answer is: volume of H₂SO₄ is 42.1 mL.<span>
Chemical reaction: H</span>₂SO₄ + 2NaOH → Na₂SO₄ + 2H₂O.<span>
c(H</span>₂SO₄) = 0,4567 M = 0,4567 mol/L.<span>
V(NaOH) = 30 mL </span>÷ 1000 mL/L <span>= 0,03 L.
c(NaOH) = 0,321 M = 0,321 mol/L.
n(NaOH) = c(NaOH) · V(NaOH).
n(NaOH) = 0,321 mol/L · 0,030 L.
n(NaOH) = 0,00963 mol.
From chemical reaction: n(H</span>₂SO₄) : n(NaOH) = 1 : 2.<span>
n(H</span>₂SO₄) = 0,01926 mol.<span>
V(H</span>₂SO₄) = n(H₂SO₄) ÷ c(H₂SO₄).<span>
V(H</span>₂SO₄) = 0,01926 mol ÷ 0,4567 mol/L.<span>
V(H</span>₂SO₄<span>) = 0,0421 L = 42,1 mL.</span>