The insulin and the glucagon are the two hormones that maintain the blood glucose level in the body. The insulin decreases the blood glucose level whereas glucagon increases the blood glucose level.
The lipolysis increases the blood glucose level level that works as the antagonistic to the insulin functioning. The levels of lipids start increases in the blood. To counteract this effect, the uptake of fat in body can cause disease like chronic liver disease due to the abnormal level of the lipids in the blood as well as in the liver.