You didn't really provide us with any options? It must be noted that generally, the structure of the skeletal system also dictates its function. With that I mean that having bones and a skeletal system enables us to move more efficiently and to have the pose which we have.
Answer: In order to compensate for the low partial pressure of oxygen at altitude, the human body undergoes a number of physiological changes. A vital component in this process is the increase in the concentration of circulating haemoglobin. The role of HIF‐1α, erythropoietin and red blood cells in this acclimatisation process is described, together with the fall in plasma volume that increases the concentration of haemoglobin in the early stages of hypoxic exposure.
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The answer is calories really sorry if it is wrong