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We can consider a chemical to be safe if it does not contain any harmful substances such as nitrogen, harmful acids, or even excessive heat. Other chemicals such as the chemicals used in food products like, for example, citric acid, is not so harmful.
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Answer is: C. nuclear fission.
Nuclear fission is a nuclear reaction or a radioactive decay where nucleus of atom split into smaller ligher nuclei.
Nuclear fission is exothermic reaction which release large amounts of energy (electromagnetic radiation or as kinetic energy, which heat reactors where fission reaction take place).