Rapid weight loss.
Recurring fever or profuse night sweats.
Extreme and unexplained tiredness.
Prolonged swelling of the lymph glands in the armpits, groin, or neck.
Diarrhea that lasts for more than a week.
Sores of the mouth, anus, or genitals.
Pneumonia.
A major way to prevent running injuries is to stretch and warm up before running, and cool down after.