Answer:
Climate and slavery
Explanation: Slaves were the main reason that there was food before the end when Abraham was president. Climate and slavery can change how the crops were grown. I'd also say the geography was messed up then due to the climate. (sorry if wrong Q-Q)
The answer is choice B.
Nondisjunction happens when the chromosomes don't separate correctly during meiosis, which can result in an extra copy of certain chromosome.
I hope this helped a little bit.