1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
Hitman42 [59]
3 years ago
6

Two drugs, tested in an in vitro system, turn out to have equal affinity for the same receptor and intrinsic activities of 1.0 a

nd 0.25 respectively. Which of the following would be the correct percent of the maximal response, when both drugs are present at the same time in maximally effective concentrations?A. 12.5%B. 25%C. 62.5%D. 75%E. 100%
Health
1 answer:
igomit [66]3 years ago
4 0

Answer: The correct answer is C. 62.5%

Explanation:

Since the two drugs have equal affinity for the same receptor, when both are present at the same time in maximally effective concentrations, one half of the receptors will be occupied by the first drug and one half by the second drug. Since the intrinsic activity of the first drug is 1.0, each receptor occupied by this drug will be activated 100% and therefore the total response of one half of the receptors will be 50% of the maximal response. By the same token, since the Intrinsic activity of the second drug is 0.25, each receptor occupied by this drug will be activated 25% and so the total response of the other half of the receptors will be 12.5% of the maximal response. Therefore the response of all receptors will be 50% +12.5%, that is 62.5 % of the maximal response.

You might be interested in
Human resource is the most significant factor for development. Justify the statement.​
Dovator [93]

Answer:

It is the most important because people are very important to the development of the country.

Explanation:

People are doing the work. We need the people to work at stores, build, mine, etc. The people of today are the ones that are building the industry making it a better place to live in. People are also important for the research, development, and engineering.

7 0
2 years ago
How is cardio exercise best described?
garri49 [273]
According to verywellfit “Cardio exercise simply means that you're doing a rhythmic activity that raises your heart rate into your target heart rate zone, the zone where you'll burn the most fat and calories.”
5 0
2 years ago
Select the correct answer from each drop-down menu.
Furkat [3]

Answer:

histamin, wider, swelling

Explanation:

Inflammation is defined as the response of body's immune system to a stimulus (invasion of pathogen or any injury). Some of the inflammatory responses are swelling of wound, redness of wound and itching at injured area et-cetra.

Upon any injury, the injured cells releases a chemical including histamin which causes vasodilation and increased permeability of blood vessels. This chemical recruit white blood cells to the damaged area and initiate the healing process. This chemical allows the local blood capillaries more wider due to vasodilation effect. Under the influence of histamin, the endothelium lining become leaky and allows movement of fluid to interstitial tissue spaces. When the extra fluid moves from capillaries to damaged tissue, it causes swelling or called edema.

The white blood cells initiate phagocytosis of pathogens at injured area and destroy the pathogens. Due to increased pressure from edema and toxins released by pathogens, the pain sensation prolongs, even while the body is repairing the tissue.

Hence, the correct answers are histamin, wider, swelling.

5 0
3 years ago
In what two ways does the poem’s structure match the movements of the turtle it describes?
Dmitriy789 [7]

Answer:

-they both have uneven movements

-they both stop and unevenly

Explanation:

Just did on edge-nuity and they are correct :)

5 0
3 years ago
Read 2 more answers
One way parents and guardians can influence technology use is to model proper use for their children. What outcome would you exp
uysha [10]

Answer: Ok so there's no number or letter answers but the answer is C. Hope this helps :)

Explanation:

3 0
3 years ago
Other questions:
  • How can refusal skills help you say no to tobacco
    6·1 answer
  • Americans often lead stressful lives. The stresses come from work, school, family and social pressures. The long term effects of
    15·2 answers
  • What is the best strategy for resisting peer pressure to take drugs?
    10·2 answers
  • Dental assistant A says a child's first dental visit should be around the age of 4, when children start to brush their own teeth
    11·2 answers
  • Although 3-year-old Adam happily explores the attractive toys located in the dentist's waiting room, he periodically returns to
    9·1 answer
  • If left untreated both chlamydia and trichomoniqsis can lead to
    14·1 answer
  • Do you think it is a good idea to have a group go to raves and dance clubs and test Ecstasy to make sure it is really Ecstasy an
    7·2 answers
  • John runs the silo blower for 5 minutes before entering the silo to remove silo gas. Is this safe or unsafe?
    6·1 answer
  • Why is drum used while porting PT ?​
    7·1 answer
  • What essential nutrients are the building blocks for bones, skin, and blood?
    10·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!