Question

In what ways would adding the nabh4 too early would interfere with your reaction?

Answer 1

NaBH4 is blind + will reduce other functional groups.

Functional groups:

The aldehyde group in o-vanillin would be converted to alcohol if it had been added during step one (imine production). Because the carbon is not sufficiently nucleophilic, p-toluidine would not attack and imine would not form in the maximum yield.

Regardless of the other atoms in the molecule, a functional group is a collection of atoms that have specific chemical characteristics. Covalent bonds bind the atoms in a functional group to the other molecules in the molecule as well as to one another. Examples: Alcohol, Aldehyde, Ketone, Carboxylic acid, Halogens, Double & Triple covalent bonds.

A carbonyl in which the carbon atom is linked to at least one hydrogen atom is called an aldehyde. An R-group or a hydrogen atom could be the other group joined to the carbonyl. Aldehydes are a highly reactive form of carbonyl because of the tiny size of the hydrogen atom, which makes it relatively simple for other molecules to approach the partial positive charge on the carbonyl carbon. Aldehydes are adaptable reactants used in numerous different organic synthesis processes. Numerous aldehydes also have unique tastes and odors.

Learn more about functional group here:

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