The coefficient of performance (cop) of a refrigerator is defined as the ratio of " the work necessary to heat or cool something usefully."
The usable heating or cooling delivered to work required ratio, also known as the coefficient of performance, or COP, of a heat pump, refrigerator, as well as air conditioning system. Higher efficiency, less energy (power) usage, and thus reduced operational costs are all related to higher COPs.
Coefficient of performance formula:

where, K = Coefficient of performance,
= heat of pumps output,
= work required by the system.
It is refrigeration's coefficient of performance (COP) will always be greater than 1.
Therefore, the coefficient of performance (cop) of a refrigerator is defined as the ratio of " the work necessary to heat or cool something usefully."
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The number of Ml of a 0.40 %w/v solution of ,nalorphine that must be injected to obtain a dose of 1.5 mg is calculated as below
since M/v% is mass of solute in grams per 100 ml
convert Mg to g
1 g = 1000 mg what about 1.5 mg =? grams
= 1.5 /1000 = 0.0015 grams
volume is therefore = 100 ( mass/ M/v%)
= 100 x( 0.0015/ 0.4) = 0.375 ML