Answer:
Harmful mutations may cause genetic disorders or cancer. A genetic disorder is a disease caused by a mutation in one or a few genes. A human example is cystic fibrosis. A mutation in a single gene causes the body to produce thick, sticky mucus that clogs the lungs and blocks ducts in digestive organs.
Mutations arise spontaneously at low frequency owing to the chemical instability of purine and pyrimidine bases and to errors during DNA replication. Natural exposure of an organism to certain environmental factors, such as ultraviolet light and chemical carcinogens (e.g., aflatoxin B1), also can cause mutations.
only a small percentage of mutations cause genetic disorders—most have no impact on health or development. For example, some mutations alter a gene's DNA sequence but do not change the function of the protein made by the gene.
Marijuana can increase a person's hearth rate almost 100%.
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You would definitely underweight. The villi in your small intestines increase intestinal absorptive surface area approximately 30-fold and 600-fold respectively. This provides exceptionally efficient absorption of nutrients in the lumen. This increases the surface area for food to be absorbed. So if there were to be less villi you would underweight.