Question

The recommended maintenance dose of aminophylline for children is 1 mg/kg/h by injection. If 10 mL of a 25-mg/mL solution of aminophylline is added to a 100-mL bottle of dextrose injection, what should be the rate of delivery, in milliliters per hour, for a 40-lb child?

Answer 1

Answer:

The rate of delivery 7.256 mL/hour for a 40-lb child.

Explanation:

The recommended maintenance dose of aminophylline for children = 1 mg/kg h

Mass of children = 40 lb = 18.14 kg

1 lb = 0.453592 kg

Amount of aminophylline for children to be given to in a hour:

= 1 mg/kg h  × 18.14 kg × 1 h = 18.14 mg

If 10 mL of a 25 mg/mL solution of aminophylline is added to a 100 mL bottle of dextrose injection.

Amount of dose in 10 mL of 25 mg/mL solution of aminophylline.

The value of dose in which 18.14 mg of dose is present in :

$\frac{10}{25}\times 18.14 mL=7.256 ml$

So, in a an hour 7.256 volume of the solution of aminophylline should delivered to the childrenin an hour.

The rate of delivery 7.256 mL/hour for a 40-lb child.