That means that 1 mol of molecules is 6.022 * 10^23 molecules, so 4 moles is 4 * 6.022 * 10^23 molecules = 24.088 * 10^23 molecules = 2.4088 * 10^24 molecules.
Well, if u had a spilled liquid in there (we'll simply go with water) and you had the freezer at a cold temperature it would change (like,icycles on trees when it's snowing)