Question

The same, unknown bacteria is isolated from 20 sick individuals. Their samples were grown in culture and then placed in 10 healthy mice. Those mice started to show signs of a heightened immune response. According to Koch’s postulates what is the next step in determine whether the bacteria is pathogenic?

Answer 1

Answer:

To isolate the microorganism from the mice and determine if it is identical to the original unknown bacteria.

Explanation:

The next step to take is to isolate the microorganism from the mice and determine if it is identical to the original unknown bacteria.

Koch's postulates opines four criterion for which a microbe will be regarded as a causative agent of a disease if the following takes place.

That, the microorganism should be present in all the organism suffering from the disease. That these isolated microorganism are meant to be grown in a pure culture. After being grown in the culture, they  should be reintroduced in the susceptible but healthy host. In conclusion, from the experimental host, the microorganism must be re-isolated. Hence, cultured to see whether it is identical to the original specific microorganism.