Answer:
1,2 and 4 are correct
Explanation:
Enzymes that show cooperativity are defined as Allosteric enzymes. This cooperativity is of several types.
1) homotropic/homoallestery - positive cooperation
2) heterotropic/heteroallestery - negative cooperation
Activity of allosteric enzymes is regulated by other molecules (effector molecules)
Hence, statement 1 and 2 are correct.
Binding curve of allosteric enzymes:
For cooperative binding, binding curve is Sigmoidal curve
For non cooperative binding, binding curve is Hyperboilc curve.
Hence, statement 3 is wrong.
Allosteric enzymes have multiple active sites.
Allosteric enzymes are often multi sub unit proteins.
Hence, statement 4 is correct.