The correct answer is option C
The demand for a better life increased the pollution in the society. The increased pollution in the environment led to many health problems.
The Nuclear power plant creates radioactivity and thermal pollution.
The water used in the nuclear power plants is very warm and causes thermal pollution as it is released into water bodies.
The nuclear power plant uses radioactive substances like uranium and the waste that is left is radioactive waste.
Yes, it is true that Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis.
Enhancer of zeste homolog 2 (EZH2), a key histone methyltransferase and EMT inducer, is overexpressed in diverse carcinomas, including breast cancer.
However, the molecular mechanisms of EZH2 dysregulation in cancers are still largely unknown. Here, we discover that EZH2 is asymmetrically dimethylated at R342 (meR342-EZH2) by PRMT1.
meR342-EZH2 was found to inhibit the CDK1-mediated phosphorylation of EZH2 at T345 and T487, thereby attenuating EZH2 ubiquitylation mediated by the E3 ligase TRAF6.
We also demonstrate that meR342-EZH2 resulted in a decrease in EZH2 target gene expression, but an increase in breast cancer cell EMT, invasion and metastasis.
Moreover, we confirm the positive correlations among PRMT1, meR342-EZH2 and EZH2 expression in the breast cancer tissues. Finally, we report that high expression levels of meR342-EZH2 predict a poor clinical outcome in breast cancer patients.
Our findings may provide a novel diagnostic target and promising therapeutic target for breast cancer metastasis.
Learn more about breast cancer here : brainly.com/question/6747562
#SPJ4
Small, highly concentrated cell organelles that produce proteins are called <span>ribosomes. Ribosomes can be free-floating or attached to endoplasmic reticulum.</span>
A eukaryotic cell has a plasma membrane, cytoplasm, and ribosomes. However, unlike prokaryotic cells, eukaryotic cells have a membrane-bound nucleus.
*Got this info from the internet*
