Enzymes are characterized to have weak bonds because their tertiary structure could easily bend and break because it will have to adjust to the shape of the substrate. It could be done via induced fitting or lock-and-key theory. These weak bonds are intermolecular forces like the London forces, electrostatic interactions and hydrogen bonding.
2.998e^8 is how I would write it. If you want it with the least amount of decimals, use 3e^8