Question

Achondroplasia is a common form of dwarfism caused by an autosomal dominant mutation in the fibroblast growth factor receptor 3 (FGFR3) gene. Two copies of the mutant gene are invariably fatal before or shortly after birth. If a person with achondroplasia marries a person of normal height, what is the probability that they will have a child with achondroplasia?

Answer 1

Symptoms of Achondroplasia

Explanation:

• Achondroplasia is caused about by a quality change (transformation) in the FGFR3 gene
• The FGFR3 quality makes a protein called fibroblast development factor receptor 3 that is engaged with changing over ligament to bone
• FGFR3 is the main quality known to be related with achondroplasia Achondroplasia is acquired in an autosomal predominant example, which implies one duplicate of the adjusted quality in every cell is adequate to cause the confusion
• In the rest of the cases, individuals with achondroplasia have acquired an adjusted FGFR3 quality from a couple of affected parents