Question

Glycolysis produces NADH . However, NADH cannot cross the inner mitochondrial membrane to be used in the electron transport chain (respiratory chain). The malate–aspartate shuttle in some animal cells transfers electrons from cytosolic NADH to the matrix. How is oxaloacetate modified to a form that can be transported out of the matrix? transamination isomerization dehydrogenation uncoupling Which compound is transported across the inner membrane in exchange for malate? NADH α‑ketoglutarate aspartate glutamate oxaloacetate

Answer 1

Answer: 1.) oxaloacetate can be modified to a form that can be transported out of the matrix through TRANSAMINATION.

2.) The compound that is transported across the inner membrane in exchange for malate is α‑KETOGLUTARATE.

Explanation:

The malate- aspartate shuttle is a system that allows electrons to move across membrane between the cytosol and mitochondrial matrix. The electrons generated during glycolysis such as NADH cannot cross the inner mitochondrial membrane to be used in the electron transport chain (respiratory chain). Therefore through reduction- oxidation reactions, the malate- aspartate shuttle regenerates NADH inside the mitochondrial matrix which can be used to pass electrons to the electron transport chain so that ATP can be synthesized.