2.Which of the alcohols listed below would you expect to react most rapidly with PBr3?A)CH3CH2CH2CH2CH2CH2OHB)(CH3CH2)2CH(OH)CH2
CH3C)(CH3CH2)2CHOHCH3D)(CH3CH2)3COHE)(CH3CH2)2C(CH3)OH
1 answer:
Answer:
A) CH3CH2CH2CH2CH2CH2OH
Explanation:
For this question, we have the following answer options:
A) CH3CH2CH2CH2CH2CH2OH
B) (CH3CH2)2CH(OH)CH2CH3
C) (CH3CH2)2CHOHCH3
D) (CH3CH2)3COH
E) (CH3CH2)2C(CH3)OH
We have to remember the<u> reaction mechanism</u> of the substitution reaction with . <em>The idea is to generate a better leaving group in order to add a "Br" atom.</em>
The attacks the "OH" generation new a bond to P (O-P bonds are very strong), due to this new bond we will have a better leaving group that can remove the oxygen an allow the attack of the Br atom to generating a new C-Br bond. This is made by an <u>Sn2 reaction</u>. Therefore we will have a faster reaction with <u>primary substrates</u>. In this case, the only primary substrate is molecule A. So, <em>"CH3CH2CH2CH2CH2CH2OH"</em> will react faster.
See figure 1
I hope it helps!
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Answer:
See explanation below
Explanation:
The question is incomplete, cause you are not providing the structure. However, I found the question and it's attached in picture 1.
Now, according to this reaction and the product given, we can see that we have sustitution reaction. In the absence of sodium methoxide, the reaction it's no longer in basic medium, so the sustitution reaction that it's promoted here it's not an Sn2 reaction as part a), but instead a Sn1 reaction, and in this we can have the presence of carbocation. What happen here then?, well, the bromine leaves the molecule leaving a secondary carbocation there, but the neighbour carbon (The one in the cycle) has a more stable carbocation, so one atom of hydrogen from that carbon migrates to the carbon with the carbocation to stabilize that carbon, and the result is a tertiary carbocation. When this happens, the methanol can easily go there and form the product.
For question 6a, as it was stated before, the mechanism in that reaction is a Sn2, however, we can have conditions for an E2 reaction and form an alkene. This can be done, cause the extoxide can substract the atoms of hydrogens from either the carbon of the cycle or the terminal methyl of the molecule and will form two different products of elimination. The product formed in greater quantities will be the one where the negative charge is more stable, in this case, in the primary carbon of the methyl it's more stable there, so product 1 will be formed more (See picture 2)
For question 6b, same principle of 6a, when the hydrogen migrates to the 2nd carbocation to form a tertiary carbocation the methanol will promove an E1 reaction with the vecinal carbons and form two eliminations products. See picture 2 for mechanism of reaction.
Assume 1 tsp is approximately can hold 5 mL liquid.
Given the dose of medicine = 1.5 tsp
Converting 1.5 tsp to mL:
= 7.5 mL
Given the specific gravity of the medicine = 1.23
That means density of the medicine with respect to water will be 1.23
As the density of water is 1 g/mL
We can take density of the medicine to be 1.23 g/mL
Calculating the mass of medicine in grams:
9.225 g medicine is present in one dose.