For an amino acid such as aspartic acid, what impact would you expect a neighboring carboxylic acid to have on the apparent pKa

Question

noname [10]

3 years ago

5

For an amino acid such as aspartic acid, what impact would you expect a neighboring carboxylic acid to have on the apparent pKa

value of the side chain?

Chemistry

1 answer:

tekilochka [14] · Answer 1 · 2022-05-06T11:24:49+03:00

Answer:

The apparent pKa value for aspartic acid increases

Explanation:

The apparent pKa value for aspartic acid increases. Due to the presence of one negative in close proximity to another negative charge, it causes charge-to-charge repulsion which in turn leads to the increase in pKa values.