Question

Show how you could prepare each of the following amines from benzaldehyde by reductive amination:

Answer 1

Answer:

Check explanation.

Explanation:

Reductive amination is also known as reductive alkylation. Reductive amination is an good chemical reaction for the conversion of of carbonyl group into amine.

These are the steps to follow for the reaction;

(1). Step one: carbonyl group(either an aldehyde or a ketone) is used to convert amine to form an imine. The pH of the reaction should be slightly acidic.

(2). Step 2: the imine from step one is then converted into iminium ion under acidic condition too(for protonation).

(3). Step 3: the iminium ion is then reduced to the amine.

The equation of reaction are in the attached file.

Note: the attached picture is labelled (A) to (D).

Reaction A is the reaction of benzaldehyde with Benzylamine, B is the reaction of benzaldehyde with dibenzylamine, C is the reaction of benzaldehyde with N,N-Dimethylbenzylamine and D is the reaction of benzaldehyde with N-Benzylpiperidine.