Emphysema is a lung condition that causes shortness of breath.
Explanation:
in people with emphysema, the air sacs in the lungs (alveoli) are damaged. Over time, the inner walls of the air sacs weaken and rupture — creating larger air spaces instead of many small ones.
The diferrence between the two is Santa Fe Trail was used by traders to cross the Great Plains and the Old Spanish Trail was used by traders to reach California.