Answer:
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Explanation:
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<em>Phenolphthalein is often used as an indicator in acid–base titrations. For this application, it turns colorless in acidic solutions and pink in basic solutions. It belongs to the class of dyes known as phthalein dyes.</em>
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Answer:
Pilot scale up
Explanation:
Preformulation studies are carried out on candidate drug molecules that show sufficient pharmacological promise in animal model(pharma approach).
It involves preliminary study of the properties of a drug which is considered a potentially active ingredient against a particular disease condition.
Scale-up is the term used to refer to the increase in the batch size of a product. This is only done after a drug has been proven successful against the target disease after extensive pilot studies.
Scale-up is the last operation carried out when a drug has passed through all stages. It is not included in preliminary preformulation studies
Answer:
Explanation:
a) 4-nitrobenzoic acid pKa= 3.41
benzoic acid pKa= 4.19
4-chlorobenzoic acid pKa= 3.98
b) benzoic acid pKa= 4.19
cyclohexanol pKa= 18.0
phenol pKa= 9.95
c) 4-Nitrobenzoic acid pKa= 3.41
4-nitrophenol pKa= 7.15
4-nitrophenylacetic acid pKa= 3.85