Answer:
D. both use a strong, non-nucleophilic base such as LDA and use a low temperature.
Explanation:
The more stable enolate is the thermodynamic enolate, and a less stable is known as the kinetic enolate.
The less stable enolate has a less substituted product, while the more stable product has a more substituted product.
Now, to form a kinetic enolate, we need to choose a strong, non-nucleophilic base such as LDA to attract hydrogen from the less substituted site. However, an increase in temperature results in an increase in a reaction, which leads to the formation of a stable product.
So, to form the kinetic enolate, a low temperature will be required.
Thus, To form a kinetic enolate, both use a strong, non-nucleophilic base such as LDA and use a low temperature.
