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Dmitrij [34]
2 years ago
13

What is the benefit of substrate channeling? The PDH active site forms in the hydrophobic core of the complex instead of a surfa

ce‑exposed region. Reaction intermediates move to sequential active sites faster than the diffusion constant. Every intermediate or product made by the PDH complex enters the citric acid cycle as a substrate. The PDH complex sequesters excess substrate to use at later time. Intermediates of a multistep reaction sequence do not dissociate from the enzyme complex.
Chemistry
1 answer:
aleksklad [387]2 years ago
5 0

Answer:

Intermediates of a multistep reaction sequence do not dissociate from the enzyme complex.

Explanation:

Substrate channeling is the process in which intermediates produced in an enzymatic reaction is transferred to another enzyme or active in a reaction pathway without the substrate having to dissociate from the enzymes active sites into the reaction medium or solution.

Benefits of substrate channeling include:

  • intermediates of a multistep reaction sequence do not diffuse away from the catalytic sites of enzymes in the pathway thereby ensuring that their concentration remains high
  • there is  greater control of the flow metabolites in the pathway
  • other competing enzymes for a common substrate do not make use of the substrates
  • increased efficiency of the catalytic process

Substrate channeling is observed in the pyruvate dehydrogenase complex reaction which oxidizes pyruvate to acetyl-CoA.

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Answer:

\large \boxed{\textbf{609 kJ}}  

Explanation:

The formula for the heat absorbed is

q = mCΔT

Data:

m = 2.07 kg

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T₂ = 191 °C

C = 1.75 J·°C⁻¹g⁻¹

Calculations:

1. Convert kilograms to grams

2.07 kg = 2070 g

2. Calculate ΔT

ΔT = T₂ - T₁ = 191 - 23  = 168 °C

3. Calculate q

q = \text{2070 g} \times 1.75 \text{ J$^{\circ}$C$^{-1}$g$^{-1}$} \times 168 \,^{\circ}\text{C} = \text{609 000 J} = \textbf{609 kJ}\\\text{The heat energy required is }\large \boxed{\textbf{609 kJ}}

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3 years ago
SCIENCE<br> why is it important to distinguish the two types of crust?
Yuri [45]

Answer:

It is important to identify it because the two types of crust are made up of two different types of rock

Explanation:

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4 0
3 years ago
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in order to find the molar mass of an unknown compound, a research scientist prepared a solution of 0.930 g of an unknown in 125
PtichkaEL [24]

Answer:

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Explanation:

Let's apply the formula for freezing point depression:

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Difference between the freezing T° of pure solvent and freezing T° of solution

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These are the moles in 1 kg of solvent so let's find out the moles in our mass of solvent which is 0.125 kg

0.0516 mol/kg . 0.125 kg = 6.45×10⁻³ moles. Now we can determine the molar mass:

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Answer:

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