The histidine imidazole side chain has a pka of 6.04. To illustrate the predominant structures for histidine at (i) ph 4, (ii) ph 8, and (iii) ph 12, we have the pictures attached below. The first one indicates structure at ph 4, second one indicates ph 8 and third indicates ph 12.
<h3>What is stereochemistry? </h3>
The study of stereochemistry is focused on stereoisomers, which by definition have the same molecular formula and sequence of bonded atoms (constitution) but differ in the three-dimensional orientations of their atoms in space.
Stereochemistry is a subfield of chemistry that deals with the relative spatial arrangement of atoms that form the structure of molecules and their manipulation. Because the prefix “stereo- “denotes “three-dimensionality,” it is also referred to as “3D chemistry.”
One crucial area of stereochemistry is the study of chiral molecules. Stereochemistry covers the entire range of organic, inorganic, biological, physical, and particularly supramolecular chemistry.
The study of stereochemistry involves techniques for identifying and describing these interactions, as well as the impact these relationships have on the physical or biological characteristics of the molecules in question.
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