Yeah of-course!! It's valency by group most of the chemical property like electronegativity, ionization energy etc. by the combination of groups and periods...
Both strong acid and strong base will alter the solubility and the nature of a protein. This is because, adding a strong acid or base to a protein will drastically change the pH of the protein and this will leads to formation of precipitation and denaturation of the protein.
I think it’s B but not 100% sure