<h3><u>Full Question:</u></h3>
The following compound has been found effective in treating pain and inflammation (J. Med. Chem. 2007, 4222). Which sequence correctly ranks each carbonyl group in order of increasing reactivity toward nucleophilic addition?
A) 1 < 2 < 3
B) 2 < 3 < 1
C) 3 < 1 < 2
D) 1 < 3 < 2
<h3><u>Answer: </u></h3>
The rate of nucleophilic attack of carbonyl compounds is 2<3 <1.
Option B
<h3><u>Explanation. </u></h3>
Nucleophilic attack is explained as the attack of an electron rich radical to a carbonyl compound like aldehyde or a ketone. A nucleophile has a high electron density, so it searches for a electropositive atom where it can donate a portion of its electron density and become stable.
A carbonyl compound is a
hybridized carbon atom with a double bonded oxygen atom in it. The oxygen atom pulls a huge portion of electron density from carbon being very electropositive.
In a ketone, there are two factors that make it less likely to undergo a nucleophilic attack than aldehyde. Firstly, the steric hindrance of two carbon groups being attached with the carbonyl carbon makes it harder for the nucleophile to approach. Secondly, the electron push by the carbon groups attached makes the carbonyl carbon a bit less electropositive than the aldehyde one. So aldehydes are more reactive towards a nucleophilic addition reaction.
The answer is salinity, salinity is the saltiness or dissolved inorganic salt content of a body of water.
Answer: 8.30 g of calcium sulfate are produced from 10 grams of lithium sulfate.
Explanation:
To calculate the moles :
According to stoichiometry :
1 mole of
require = 1 mole of
Thus 0.061 moles of
will require=
of
Thus
is the limiting reagent as it limits the formation of product and
is the excess reagent.
As 1 mole of
give = 1 mole of
Thus 0.061 moles of
give =
of
Mass of
Thus 8.30 g of calcium sulfate are produced from 10 grams of lithium sulfate.
Answer:
pH = 4.17
Explanation:
According to the molar concentration you stated, pH of the solution is: 4.17
Remember that pH = - log [H⁺]
and [H⁺] = 10^-pH
When:
pH > 7 → Basic solution
pH = 7 → Neutral solution
pH < 7 → Acid solution