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lianna [129]
3 years ago
9

Match the cofactors below with their roles in the pyruvate dehydrogenase complex reaction.

Chemistry
1 answer:
tiny-mole [99]3 years ago
8 0

Cofactors:
A. Coenzyme A (CoA-SH)
B. NAD+
C. Thiamine pyrophosphate (TPP)
D. FAD
E. Lipoic acid in oxidized form

Roles:
E... Attacks and attaches to the central carbon in pyruvate.
A...Oxidizes FADH2.
C...Accepts the acetyl group from reduced lipoic acid.
D... Oxidizes the reduced form of lipoic acid.
B... Initial electron acceptor in oxidation of pyruvate.
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Note the following images:

Non-bonded electron pairs are in plane of parent geometry and Fluorides covalently bonded to central element Chloride forming the T-shaped geometry.

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