What evidence do you have that tpgs-750m increases the reaction rate? How does tpgs-750m act to increase the reaction rate?
1 answer:
TPGS-750 M conducts reaction under lower temperature then the reactions carried out in organic solvents.
<h3>What is tpgs-750m ?</h3>It is a chemical molecule of the second generation known as an amphiphile, with both hydrophilic and lipophilic qualities.
- In contrast to any other organic solvent, water is used for transition metal catalysed cross-coupling, making TPGS-750M a second generation surfactant with physical features that encourage this process.
- The hydrophilic portion of TPGS-750M, which is utilised in medicine, is made of Poly(ethylene glycol), and the hydrophobic portion is made of the vitamin E compound alpha-tocopherol.
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The structure of the alkyl bromides used in a malonic ester synthesis of ethyl 2-methyl-4-pentenoate are as drawn in the attached image.
<h3>Ethyl 2-methyl-4-pentenoate by Malonic ester synthesis.</h3>The malonic ester synthesis is a chemical reaction characterized by the alkylation of diethyl malonate or a similar ester of malonic acid at the carbon alpha (directly adjacent) to both carbonyl groups, and subsequently converted to a substituted acetic acid.
Hence, it follows from the structure of Ethyl 2-methyl-4-pentenoate that the alkyl bromides used are Ethyl bromide and methyl bromide.
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