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alexandr402 [8]
1 year ago
5

Malonate is a competitive inhibitor of succinate dehydrogenase. If malonate is added to a mitochondrial preparation that is oxid

izing pyruvate as a substrate, which compound would you expect to decrease in concentration?.
Chemistry
2 answers:
fiasKO [112]1 year ago
5 0

In competitive inhibitor <u>fumarate </u>decrease in concentration.

A competitive inhibitor is any molecule that can bind to the energetic site of an enzyme with enough affinity such that it could compete with the enzyme's natural substrate and decrease enzyme hobby as a end result.

An instance of a competitive inhibitor is the antineoplastic drug methotrexate. Methotrexate has a structure similar to that of the vitamin folic acid. It acts through inhibiting the enzyme dihydrofolate reductase, stopping the regeneration of dihydrofolate from tetrahydrofolate.

In competitive inhibition, an inhibitor that resembles the ordinary substrate binds to the enzyme, typically at the active web site, and prevents the substrate from binding. At any given second, the enzyme may be sure to the inhibitor, the substrate, or neither, but it can not bind each on the equal time.

Learn more about competitive inhibitor here:- brainly.com/question/14944549

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NARA [144]1 year ago
3 0

Malonate is an aggressive inhibitor of succinate dehydrogenase. If malonate is added to a mitochondrial education this is oxidizing pyruvate as a substrate, it is lower in attention<u> </u><u>Fumarate</u><u>.</u>

<u />

Succinate dehydrogenase is also known as mitochondrial complicated II, and inhibition of succinate dehydrogenase by means of dimethyl malonate has been said to suppress the production of pro-inflammatory cytokines.

Fumaric acid is an organic compound with the system HO₂CCH=CHCO₂H.  It has a fruit-like taste and has been used as a meal additive. . The salts and esters are referred to as fumarates. Fumarate also can consult with the C ₄H ₂O²⁻ ₄ ion.

Learn more about Fumarate here

brainly.com/question/17098570

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You might be interested in
In which set do all elements tend to form anions in binary ionic compounds? li, na, k n, o, i c, s, pb k, fe, br?
pav-90 [236]

Atoms or molecule after gaining of electron possesses negative charge and is known as anion.

For the given sets:

  • Li, Na, K

The given elements are alkali metals and have tendency to lose electrons easily and form cations.

  • N, O, I

The given elements are non-metals and are electronegative. So, they gain electrons easily and form anion.

  • C, S, Pb

Carbon has tendency to form bond by sharing of electrons, Sulfur has tendency to gain electrons and form anion whereas Lead has tendency to lose electron.

  • K, Fe, Br

Potassium and Iron has tendency to lose electron and form cation whereas Bromine has tendency to gain electron to form anion.

Hence, from the given sets, all elements of set: N, O, I have tendency to form anions in binary ionic compounds.

8 0
3 years ago
Read 2 more answers
What is the pH of a solution of 0.800 M KH2PO4, potassium dihydrogen phosphate?
Nookie1986 [14]
KH₂PO₄ hydrolyzes as;
H₂PO₄⁻ + H₂O ↔ H₃PO₄ + OH⁻
Let x amount of H₂PO₄⁻ has reacted with water then,
Kb₁ = [H₃PO₄][OH⁻] / [H₂PO₄⁻]
[H₂PO₄⁻] = 0.8-x M
Kb₁ = x² / (0.8 - x)
Given Ka₁ = 7.5 x 10⁻³
so Kb₁ = 1 x 10⁻¹⁴ / (7.5 x 10⁻³) = 1.33 x 10⁻¹²
From this information:
1.33 x 10⁻¹² = x² / 0.8
x = [OH⁻] = 1.03 x 10⁻⁶ M
pOH = - log (1.03 x 10⁻⁶) = 5.99
pH = 14 - pOH = 14 - 5.99 = 8.01 



3 0
3 years ago
PLEASE! :( Two aqueous solutions of AgNO3 and NaCl are mixed. Which of the following diagrams best represents the mixture? For s
-BARSIC- [3]

Answer:

NaCl + Ag(NO₃) --> Na(NO₃) + AgCl

Explanation:

Chemical equation:

NaCl + Ag(NO₃) --> Na(NO₃) + AgCl

The given reaction represent the double displacement reaction. Anion and cation of both reactant exchange with each others.

The anion of sodium chloride(Cl⁻) combine with cation of silver nitrate Ag⁺ and  NO₃⁻ combine with Na⁺.

The third equation is correct while others are in correct.

Double replacement:

It is the reaction in which two compound exchange their ions and form new compounds.

AB + CD → AC +BD

SORRY CAUSE IDK IF THAT HELPED :(

5 0
3 years ago
John is outstanding forward on his club select soccer team. He is know for his ball control and speed. After a game he often mak
natima [27]

Answer:

This self evaluation helps them to better his sport.

Explanation:

This is the right way to evaluate the performance of John because this sketch shows him the way he perform in the match. Due to this sketch he can better his performance and remove all the mistakes he had done in the match which results in better performance of John in the next match. This self evaluation helps them to better his sport and got new chances in order to select for a better club or national soccer team.

4 0
3 years ago
An element that is likely to have this property is; A. bromine B. carbon C. sodium D. tellurium ?
vladimir2022 [97]
The answer is D. Most common semiconducting materials are crystalline solids. A<span>morphous and liquid semiconductors are also known to be.</span>
4 0
3 years ago
Read 2 more answers
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