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sladkih [1.3K]
2 years ago
14

Choose the best option for the precursor to the tosylate intermediate Design a synthesis of cis-2-methylcyclopentyl acetate from

trans-2-methylcyclopentanol.
Chemistry
1 answer:
kumpel [21]2 years ago
8 0

Answer:

To synthesize cis-2-methylcyclopentyl from methycyclopentanol, you need to replace the acetate hydroxyl group with acetate by inverting the configuration.  

Explanation:

To understand the process, you need to understand the nucleophilic mechanism taking place in the process. This is the first stage of the process. Hydroxide is a poor leaving group, to it must be converted to a good leaving group. To effect the change, it is necessary to use p-toluenesuphate.

p-toluenesuphate is favored because this can be prepared by a reaction that alters none of the bonds attached to the stereogenic center.

The reaction of p-toluensulfonate with potassium acetate in acetic acid effects the conversion to give the final product: cis-2-methylcyclopentyl.  

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In a sulphuric acid (h2so4) - sodium hydroxide (naoh) acid-base titration, 17.3 ml of 0.126 m naoh is needed to neutralize 25 ml
katen-ka-za [31]
The balanced equation for the neutralisation reaction is as follows
2NaOH + H₂SO₄ ---> Na₂SO₄ + 2H₂O
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if 2 mol of NaOH reacts with 1 mol of H₂SO₄ 
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4 0
3 years ago
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6 0
3 years ago
Molecules that influence protein activity by binding to sites that are distinct from the active site are called ______________ _
Rudiy27
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Does the amount of methanol increase, decrease, or remain the same when an equilibrium mixture of reactants and products is subj
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Answer:

a. Methanol remains the same

b. Methanol decreases

c. Methanol increases

d. Methanol remains the same

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Explanation:

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a) The presence or absence of a catalyst makes no difference on the equilibrium position of the system hence the methanol remains constant.

b) The amount of methanol decreases because the equilibrium position shifts towards the left and more reactants are formed since the reaction is exothermic.

c) If the volume is decreased, there will be more methanol in the system because the equilibrium position will shift towards the right hand side.

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