This problem is providing us with the recommended maintenance dose of penicillin for children as 1.0 mg/kg/hr by injection. Thus, the delivery rate for a 40-pound child is required, if 10 mL of a 25 mg/mL solution of penicillin is added to a 100-mL bottle of saline. At the end, the result is 8.0 mL/hr:
<h3>Dimensional analysis:</h3>
In chemistry, dimensional analysis allows us to obtain a specific result given relevant information about it. Although a formula is not always provided, one can use the units as a reference for the calculations.
For example, this problem asks for the rate, in mL/hr, at which a child gets this dose, so the first step will be to get the mass of the child in kilograms:
![40 lb*\frac{0.4536kg}{1lb}= 18.144kg](https://tex.z-dn.net/?f=40%20lb%2A%5Cfrac%7B0.4536kg%7D%7B1lb%7D%3D%2018.144kg)
Next, we calculate the rate at which the penicillin is delivered to this child:
![1.0\frac{mg}{kg*hr} *18.144kg=18.144\frac{mg}{hr}](https://tex.z-dn.net/?f=1.0%5Cfrac%7Bmg%7D%7Bkg%2Ahr%7D%20%2A18.144kg%3D18.144%5Cfrac%7Bmg%7D%7Bhr%7D%20)
After that, we calculate the total mass of penicillin that is delivered:
![10mL*25\frac{mg}{mL} =250 mg](https://tex.z-dn.net/?f=10mL%2A25%5Cfrac%7Bmg%7D%7BmL%7D%20%3D250%20mg)
And get the new concentration once it is diluted to 100 mL:
![\frac{250mg}{10mL+100mL}=2.27\frac{mg}{mL}](https://tex.z-dn.net/?f=%5Cfrac%7B250mg%7D%7B10mL%2B100mL%7D%3D2.27%5Cfrac%7Bmg%7D%7BmL%7D%20%20)
And finally, we combine the mg/hr with the mg/mL to get the result in mL/hr as required:
![18.144\frac{mg}{hr} *\frac{1mL}{2.27mg}\\ \\=8.0\frac{mL}{hr}](https://tex.z-dn.net/?f=18.144%5Cfrac%7Bmg%7D%7Bhr%7D%20%2A%5Cfrac%7B1mL%7D%7B2.27mg%7D%5C%5C%20%5C%5C%3D8.0%5Cfrac%7BmL%7D%7Bhr%7D%20)
Learn more about dimensional analysis: brainly.com/question/10874167