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Sedaia [141]
4 years ago
13

Succinate dehydrogenase catalyzes the conversion of succinate to fumarate. The reaction is inhibited by malonic acid, which rese

mbles succinate but cannot be acted upon by succinate dehydrogenase. Increasing the ratio of succinate to malonic acid reduces the inhibitory effect of malonic acid. What is malonic acid's role with respect to succinate dehydrogenase? Malonic acid
Chemistry
1 answer:
allsm [11]4 years ago
3 0

Answer:

Here malonic acid acts as a competitive inhibitor of succinate dehydrogenase

Explanation:

Malonic acid structurally resembles succinic acid as a result the enzyme succinate dehydrogenase cannot distinguish between malonic acid and succinic acid.

      That"s why malonic acid interact with succinate dehydrogenase thereby blocking the catalytic activity of the later.

      As this mechanism is a type of competitive inhibition that"s why increasing the concentration of substrate succinic acid can reduce the inhibitory effect of malonic acid.

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8 0
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SashulF [63]

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The energy that a substance has available for utilization in a chemical reaction or transformation is known as the Gibbs free energy. Things frequently change into other things that have less Gibbs free energy. The Gibbs free energy change indicates whether a chemical reaction will take place spontaneously or not.

By using the formula;

ΔG° = −RTlnKp

Where,

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Substituting the value, we get,

ΔG° = −8.3 × 700 × ln(23×10⁻⁵)

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Therefore,  ΔG° for the reaction is 5.47kJ mol⁻¹.

Learn more about Gibbs free energy here:

brainly.com/question/13765848

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