the big number describes the number ratio in a chemical equation
so for example,
2H2 + O2 --> 2H2O means
2 moles of hydrogen reacts with one mole of oxygen to form 2 moles of water
and as you know, the small (subscript) number determines the number of atoms of that element in one molecule of a compound
so I believe that drawing a normal lewis structure ( O=O ) should be correct
