Alteration of the physical form of a drug outside its label is
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The new pH is 7.69.
According to Hendersen Hasselbach equation;
The Henderson Hasselbalch equation is an approximate equation that shows the relationship between the pH or pOH of a solution and the pKa or pKb and the ratio of the concentrations of the dissociated chemical species. To calculate the pH of the buffer solution made by mixing salt and weak acid/base. It is used to calculate the pKa value. Prepare buffer solution of needed pH.
pH = pKa + log10 ([A–]/[HA])
Here, 100 mL of 0.10 m TRIS buffer pH 8.3
pka = 8.3
0.005 mol of TRIS.
∴
<em> </em>inverse log 0 =
Given; 3.0 ml of 1.0 m hcl.
pka = 8.3
0.003 mol of HCL.
Therefore, the new pH is 7.69.
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