Alanine has a <u>-COOH</u> and a <u>-NH2</u> group available to form <u>hydrogen bonds</u> with water molecules.
Although there are some potential <u>dispersion forces</u> between the terminal <u>-CH3</u> group of alanine and hexane molecules, we expect the <u>hydrogen bonds</u> between alanine and water to be stronger.
Stronger intermolecular attractive forces between alanine and water lead to a more <u>negative ΔHmix</u> and more <u>negative (smaller positive)</u> ΔHsoln for water than for hexane.